Possible Reasons For Blood Clots in Novel Coronavirus Patients
Posted on 29 April 2020; 02:00 AM IST. Last Updated 29 April 2020; 01:45 PM IST.Summary: The discovery of Blood Clots in Novel CoronaVirus (covid-19) patients is very scary. This article provides some logical insights into the possible reasons for blood clots. As a precaution, it may be noted that these insights are based on pure mathematical logic, and are not derived from medical experience.
The Novel Coronavirus (covid-19) could cause blood clots, and this news is both scary and very depressing.
We could use mathematical logic and some knowledge in biology to shed more light on how and why these clots could form. Ofcourse, it is upto the medical experts to validate these theories, and to produce therapies.
The Novel Coronavirus (covid-19) is now known to cause massive inflammation in the human body. The inflammatory cells are known to cause or activate a process called angiogenesis (tumors also create this process). An advanced reader is requested to pursue the reference, available at:
https://www.jimmunol.org/content/172/7/4618
In the routine or normal life, angiogenesis is simply a process, which creates new blood vessels, and comes into play during injuries, very much like road repair and detour boards. The novel coronavirus is making the normal bodily processes go haywire. What can we infer from the knowledge at our disposal?
We could derive logical conclusions, from the biological knowledge bases, using simplified "Mathematical Logic" as follows:
Novel Corona Virus =>
Massive inflammation =>
Excessive angiogenic growth factors =>
Tissue(Blood Vessel) degradation =>
Lesions
A list of derivations such as the above, is typically called a derivation chain.
How good is the derivation? For evidence, we need to look at recent news articles.
Several recent news articles reported that some children developed such lesions in foot, and Novel coronavirus (covid-19) is the suspect. One such article is available at:
https://www.health.com/condition/infectious-diseases/coronavirus/covid-toes
The explanation for blood clots due to Novel CoronaVirus (covid-19), follows logically from "Tissue degradation".
When the body notices tissue degradation, it may be compelled to view it as an injury. So, the most natural response from the body is to heal it, i.e produce "blood clotting" agents. Now, I can add the blood clotting agents to the derivation chain as shown below. Please note that there are two chains from the "Tissue(Blood Vessel) degradation" node.
Tissue(Blood Vessel) degradation
| |
| |=> Blood Clotting Agents
| |=> Blood Clots
|
|=> Lesions
Conclusions: From the derivation tree, we could now conclude that blood clots are due to massive inflammation. If the derivation could be validated by medical experts, then therapies could focus on reducing inflammation.
Remarks: The article was written by a software professional, with the intent and hope that it could help medical experts, working overtime, in combating the Novel CoronaVirus (covid-19).